Volume 22, Issue 1 (JIAEEE Vol.22 No.1 2024)
Journal of Iranian Association of Electrical and Electronics Engineers 2024, 22(1): 0-0 |
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rafiee E. Design of an Optical Biosensor based on 2-D Photonic Crystal Structure for Diagnosis of Anemia and Acute Kidney Injury. Journal of Iranian Association of Electrical and Electronics Engineers 2024; 22 (1)
URL: http://jiaeee.com/article-1-1727-en.html
URL: http://jiaeee.com/article-1-1727-en.html
Alzahra university
Abstract: (524 Views)
In this research, a biosensor based on 2-D photonic crystals is proposed. The presented structure is made of 25*20 Si rods in the air background. Photonic bandgap and field distribution spectra are extracted considering plane wave expansion (PWE) and FDTD methods, respectively. After applying the incident signal, light wave would be propagated along the waveguide and would be transferred to outputs 1 or 2 regarding the resonant wavelength. Output 1 is considered for detection of hemoglobin concentrations in blood samples with Q-factor: (140-168), sensitivity: 1745nm/RIU, FOM: (166.1-190.7) RIU-1, and detection limit (DL): (5.2e-4 – 6.01e-4) RIU. Output 2 can also be considered for detection of creatinine concentrations in blood samples with Q-factor: (130.4-137.76), sensitivity: 1435.8nm/RIU, FOM: (110.8-126.74) RIU-1, and detection limit (DL): (7.8-4 – 8.86e-4) RIU. Considering the obtained results, physicians can diagnose anemia and acute kidney injuries in early stages and with high precisions. Finally, the proposed biosensor can be a remarkable candidate for detection of hemoglobin and creatinine in optical integrated circuits.
Keywords: Acute kidney injury, Anemia, Biosensor, Creatinine, Hemoglobin, Optical integrated circuit, Photonic crystal.
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